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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XRCC1
All Species:
10.91
Human Site:
T440
Identified Species:
24
UniProt:
P18887
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P18887
NP_006288
633
69526
T440
P
Q
T
K
T
K
P
T
Q
A
A
G
P
S
S
Chimpanzee
Pan troglodytes
XP_512717
596
65689
T403
P
Q
T
K
T
K
P
T
Q
A
A
G
P
S
S
Rhesus Macaque
Macaca mulatta
XP_001100256
645
69984
V470
N
T
P
K
Y
S
Q
V
L
G
L
G
G
R
I
Dog
Lupus familis
XP_533653
654
71801
P461
P
Q
T
K
T
K
L
P
Q
A
A
G
P
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q60596
631
68952
T439
R
P
Q
P
K
A
K
T
Q
A
A
G
P
S
S
Rat
Rattus norvegicus
Q9ESZ0
631
68817
T439
R
P
Q
P
K
A
K
T
Q
A
A
G
P
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516926
549
59237
R380
Q
P
Q
P
R
P
A
R
A
G
S
P
P
G
P
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080711
651
73244
K441
P
S
R
T
N
H
K
K
P
L
P
S
P
A
K
Zebra Danio
Brachydanio rerio
NP_001003988
615
68071
T430
E
E
T
P
K
A
K
T
P
E
K
K
P
V
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572217
614
68751
L421
T
A
I
Q
Y
R
P
L
N
Q
L
L
K
G
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001180271
512
56847
P342
S
S
S
K
S
P
Q
P
K
T
P
T
P
K
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.8
82.3
86
N.A.
86
86.5
N.A.
47.7
N.A.
53.9
51.1
N.A.
20.7
N.A.
N.A.
38.8
Protein Similarity:
100
94.1
83
88.3
N.A.
91.1
91
N.A.
56.5
N.A.
67.7
68.8
N.A.
36.9
N.A.
N.A.
55.1
P-Site Identity:
100
100
13.3
86.6
N.A.
53.3
53.3
N.A.
6.6
N.A.
13.3
20
N.A.
6.6
N.A.
N.A.
13.3
P-Site Similarity:
100
100
13.3
86.6
N.A.
53.3
53.3
N.A.
13.3
N.A.
20
33.3
N.A.
20
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
28
10
0
10
46
46
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
10
10
0
0
0
0
0
0
0
10
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
19
0
55
10
19
0
% G
% His:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
10
% I
% Lys:
0
0
0
46
28
28
37
10
10
0
10
10
10
10
19
% K
% Leu:
0
0
0
0
0
0
10
10
10
10
19
10
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
10
0
0
0
10
0
0
0
0
0
0
% N
% Pro:
37
28
10
37
0
19
28
19
19
0
19
10
82
0
10
% P
% Gln:
10
28
28
10
0
0
19
0
46
10
0
0
0
0
0
% Q
% Arg:
19
0
10
0
10
10
0
10
0
0
0
0
0
10
0
% R
% Ser:
10
19
10
0
10
10
0
0
0
0
10
10
0
46
46
% S
% Thr:
10
10
37
10
28
0
0
46
0
10
0
10
0
0
10
% T
% Val:
0
0
0
0
0
0
0
10
0
0
0
0
0
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
19
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _